Close-up of a woman receiving wrinkle-relaxing injections forehead injection at One8Clinic in Melrose Arch, Sandton, performed by a medical professional using precise technique for natural, youthful facial rejuvenation.

Top Benefits of Wrinkle-Relaxing Injections You Didn’t Know—From Experts Who Do It Daily

October 23, 20256 min read

When people think of wrinkle-relaxing injections, many only picture frozen foreheads or expressionless faces—but there's so much more to it than that. Wrinkle-relaxing injections, when performed by skilled medical professionals, are one of the safest and most effective non-surgical treatments for both aesthetic and medical concerns.

In this article, we explore what wrinkle-relaxing injections really are, how they work, and the wide-ranging benefits that continue to make them a leading treatment for facial rejuvenation at One8Clinic in Melrose Arch, Sandton, Johannesburg.

What Are Wrinkle-Relaxing Injections, and How Do They Work?

Before-and-after results of wrinkle-relaxing injections treatment at One8Clinic in Melrose Arch, Sandton, showing reduction of frown lines and smoother forehead for a refreshed, natural appearance.

Wrinkle-relaxing injections are a purified neurotoxic protein that works by blocking nerve signals to targeted muscles. When injected in tiny, safe doses, it causes temporary relaxation of specific muscles—most commonly those responsible for dynamic wrinkles (caused by repetitive movement like frowning or squinting).

This relaxation helps smooth out existing lines and prevents new wrinkles from forming, making it both a corrective and preventative treatment. Besides improving appearance, wrinkle-relaxing injections are also commonly used in medicine to help with issues like chronic migraines, excessive sweating, and jaw tension, showing their usefulness and safety when given by trained professionals.

“Wrinkle-relaxing injections doesn't erase your expressions—it softens overactive muscles to restore a calm, rested appearance without surgery.”

— Dr Steven Harris, Facial Aesthetic Doctor and International Speaker

What Are the Aesthetic Benefits of Wrinkle-Relaxing Injections?

Wrinkle-relaxing injections are most often used to smooth lines and prevent wrinkles in the following areas:

  • Forehead lines

  • Frown lines (between the eyebrows)

  • Crow’s feet (beside the eyes)

  • Bunny lines (on the nose)

  • Lip lines and downturned mouth corners

  • Neck bands (platysmal bands)

At One8Clinic, we use advanced injection techniques that preserve your natural expressions while softening signs of ageing—so you look refreshed, not frozen.

“When used conservatively and strategically, wrinkle-relaxing injections offers one of the most natural-looking ways to reduce early signs of facial ageing.”

— Journal of Cosmetic Dermatology, 2022

Woman receiving wrinkle-relaxing injections along jawline at One8Clinic in Melrose Arch, Sandton, administered by a medical professional for refined, natural facial contouring and rejuvenation.

How Long Do Wrinkle-Relaxing Injections Last?

You can expect results to begin appearing within 3–7 days after treatment, with full effects visible by the second week. On average, wrinkle-relaxing injections last:

  • 3–4 months for most aesthetic applications

  • Longer, with consistent maintenance.

Results fade gradually, so repeat treatments are needed to maintain a smoother, youthful appearance. Our medical team will work with you to schedule a plan that fits your goals and lifestyle.

With regular treatments, many patients find that their results last longer over time as the targeted muscles become trained to remain more relaxed. This allows for a more sustained youthful look and can even help reduce the severity of wrinkles in the long term.

Are There Medical Benefits of Wrinkle-Relaxing Injections?

Absolutely. Wrinkle-relaxing injections are not only cosmetic—they have a range of medically approved uses to treat conditions such as:

  • Chronic migraines

  • Excessive sweating (hyperhidrosis)

  • Teeth grinding (bruxism)

  • Jaw tension and facial pain

  • Eye twitching or lazy eye

  • Overactive bladder

If you're experiencing any of these issues, book a consultation with our medical team to explore whether wrinkle-relaxing injections might be a therapeutic solution for you.

“Wrinkle-relaxing injections have revolutionised the management of conditions like chronic migraines and hyperhidrosis—changing lives far beyond aesthetics.”

— Mayo Clinic, 2024

Medical professional at One8Clinic in Melrose Arch, Sandton, wearing a mask and holding wrinkle-relaxing injection vial during a patient consultation for safe, personalised facial rejuvenation treatment.

Are Wrinkle-Relaxing Injections Safe?

Yes—when administered by qualified medical professionals in a sterile, clinical setting. Trained doctors with a profound understanding of facial anatomy perform all wrinkle-relaxing injection procedures at One8Clinic.

Safety is our top priority. We only use authentic, approved wrinkle-relaxing injections from trusted medical suppliers.

You may experience minor side effects such as slight swelling, redness, or bruising at the injection site, but these usually subside within a day or two.

In most cases, patients are able to return to their normal activities immediately, enjoying peace of mind knowing their treatment was handled with the highest standards of care.

What Should You Expect During a Wrinkle-Relaxing Injection Treatment?

Here’s what you can expect at One8Clinic, Melrose Arch:

  • Consultation – We evaluate your facial muscles and goals to determine the most effective injection sites.

  • Treatment – The wrinkle-relaxing injection is administered via a fine needle with minimal discomfort.

  • Aftercare —You’ll receive post-treatment instructions and can typically return to work the same day.

  • Follow-up —We’re available to ensure your results are progressing as expected.

Each treatment is tailored to your facial structure, age, and aesthetic preference.

Can Wrinkle-Relaxing Injections Be Combined with Other Treatments?

Close-up of woman with smooth, glowing skin after Wrinkle-relaxing injection treatment at One8Clinic in Melrose Arch, Sandton, showcasing natural, youthful facial rejuvenation results.

Definitely. Wrinkle-relaxing injections are often combined with:

  • Dermal fillers for restoring lost volume

  • Skin boosters for improving hydration and glow

  • Thread lifts or microneedling for skin tightening and rejuvenation

Combining treatments can enhance results and address multiple concerns in a single plan. This tailored approach allows us to create a more comprehensive rejuvenation strategy that targets both dynamic wrinkles and other signs of ageing. At One8Clinic, your treatment plan is customised to your unique goals, ensuring every procedure works harmoniously for naturally balanced results.

Why Choose One8Clinic for Wrinkle-Relaxing Injections in Johannesburg?

Choosing the right provider makes all the difference. Here’s why patients trust One8Clinic:

  • Medical expertise—all injectors are doctors with clinical precision.

  • Tailored consultations – We design a plan based on your unique features.

  • Premium products: only FDA-approved, genuine wrinkle-relaxing injections are used.

  • Results-driven approach — focused on subtle, natural beauty

  • Luxury setting – Located in prestigious Melrose Arch, Sandton, Johannesburg

We don’t chase trends—we create timeless, confident results based on your natural beauty.

Doctor with stethoscope smiling alongside a patient at One8Clinic in Melrose Arch, Sandton, highlighting trusted medical expertise and personalised Wrinkle-relaxing injection treatments for natural facial rejuvenation.

Are There Any Risks Involved?

While wrinkle-relaxing injections is generally safe, potential side effects may include:

  • Minor swelling or bruising

  • Temporary drooping of the eyelid (very rare)

  • Headache or flu-like symptoms in rare cases

These risks are greatly reduced when the procedure is done by a qualified medical professional, such as those at One8Clinic. Our team follows strict safety protocols and uses only authentic, clinically approved wrinkle-relaxing injections to further minimise the chances of complications. In the unlikely event of an adverse reaction, we have the expertise and resources to address it quickly and effectively for your peace of mind.

How Much Do Wrinkle-Relaxing Injections Cost?

Pricing varies depending on:

  • The number of units required

  • Areas being treated

  • Your treatment plan

We’ll provide a detailed quote after your consultation so you know exactly what to expect. No surprises—just honest, expert care.

Medical professional at One8Clinic in Melrose Arch, Sandton, examining patient’s face during a wrinkle-relaxing injections consultation to plan safe, personalised facial rejuvenation treatment.

Are Wrinkle-Relaxing Injections Your Secret Weapon for Refreshed, Natural Beauty?

Wrinkle-relaxing injections are more than a wrinkle smoother—they’re a preventative tool, a medical solution, and a confidence booster. With the right hands and the right approach, wrinkle-relaxing injections can help you look like the best version of yourself—not someone else.

At One8Clinic, we’re here to help you feel radiant, inside and out.

📍 Visit us in Melrose Arch, Sandton, Johannesburg or contact us directly via WhatsApp to book.

🌐 Learn more or book online: www.one8clinic.co.za

Frequently Asked Questions

Will wrinkle-relaxing injections make me look frozen?

Not at all—our medical team focuses on natural, expressive results. You’ll still look like you—just smoother and more refreshed.

When should I start wrinkle-relaxing injections?

Many patients start in their late 20s to early 30s as a preventative measure, but wrinkle-relaxing injections are effective at almost any age.

Does it hurt?

Most patients report only a mild sting that passes quickly. No downtime is required.

How soon will I see results?

You’ll start noticing effects in 3–7 days, with full results by day 14.

One8Clinic, in the heart of Melrose Arch, provides comprehensive medical care and a wide range of aesthetic services and procedures.

One8Clinic

One8Clinic, in the heart of Melrose Arch, provides comprehensive medical care and a wide range of aesthetic services and procedures.

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